新氨基糖苷类抗生素——福提米星C、D和KE
Fortimicins C, D and KE, new aminoglycoside antibiotics.
作者信息
Sugimoto M, Ishii S, Okachi R, Nara T
出版信息
J Antibiot (Tokyo). 1979 Sep;32(9):868-73. doi: 10.7164/antibiotics.32.868.
PMID:511777
Abstract
From the fermentation broth of Micromonospora olivoasterospora CS-26 that produced fortimicins A and B three new aminoglycoside antibiotics, fortimicins C, D and KE, were isolated. Fortimicins C and D exhibited potent, broad spectrum antibacterial activities against Gram-positive and negative bacteria, while fortimicin KE was only weakly active.
摘要
从产生福提霉素A和B的橄榄星孢小单孢菌CS-26的发酵液中，分离出三种新的氨基糖苷类抗生素，即福提霉素C、D和KE。福提霉素C和D对革兰氏阳性菌和阴性菌均表现出强效、广谱的抗菌活性，而福提霉素KE活性较弱。
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