“Y”型单针透析过程中血液再循环的体内测量

In vivo measurement of blood recirculation during "Y" type single needle dialysis.

作者信息

Ogden D A

出版信息

J Dial. 1979;3(2-3):265-76. doi: 10.3109/08860227909063945.

Abstract

A method has been described and validated for obtaining a sample of blood, without separate venapuncture, which has the same urea and creatinine composition as systemic venous blood during hemodialysis. Using this technique, recirculation in vivo during "Y" type single needle dialysis, measured in 20 bovine fistulas, ranged from 6.9% to 56.5% and averaged 19.4% of blood flow rate as calculated from blood urea nitrogen; and averaged 22.0% with a range of 3.3% to 62.1% of blood flow rate as calculated from serum creatinine concentration. These results suggest that fistula puncture methods and devices that eliminate recirculation in the ex vivo blood circuit should be used to maximize dialysis efficiency.

摘要

已经描述并验证了一种无需单独静脉穿刺即可获取血液样本的方法，该样本在血液透析期间具有与体循环静脉血相同的尿素和肌酐成分。使用该技术，在20个牛瘘管中测量的“Y”型单针透析期间体内再循环，根据血尿素氮计算，范围为血流量的6.9%至56.5%，平均为19.4%；根据血清肌酐浓度计算，平均为血流量的22.0%，范围为3.3%至62.1%。这些结果表明，应使用消除体外血液回路中再循环的瘘管穿刺方法和装置，以最大限度地提高透析效率。