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化脓性脑膜炎患者脑脊液氨基酸异常

Abnormalities of cerebrospinal fluid amino-acids in purulent meningitis.

作者信息

Corston R N, McGale E H, Stonier C, Hutchinson E C, Aber G M

出版信息

J Neurol Neurosurg Psychiatry. 1979 Oct;42(10):881-6. doi: 10.1136/jnnp.42.10.881.

DOI:10.1136/jnnp.42.10.881
PMID:512663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC490358/
Abstract

Serial measurements were made of the cerebrospinal fluid and plasma amino-acid concentrations in 12 patients with purulent meningitis. Marked increases in the concentrations of most CSF amino-acids were found, possibly caused by altered transport mechanisms in the inflamed meninges and choroid plexuses.

摘要

对12例化脓性脑膜炎患者的脑脊液和血浆氨基酸浓度进行了系列测量。发现大多数脑脊液氨基酸浓度显著升高，这可能是由于炎症性脑膜和脉络丛中转运机制改变所致。

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Abnormalities of cerebrospinal fluid amino-acids in purulent meningitis.化脓性脑膜炎患者脑脊液氨基酸异常
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本文引用的文献

1
Accumulation of glutamic acid in isolated brain tissue.谷氨酸在离体脑组织中的蓄积。
Biochem J. 1949;44(4):410-8.
2
AN ELECTROPHORETIC STUDY OF THE PROTEIN COMPONENTS IN CEREBROSPINAL FLUID AND THEIR RELATIONSHIP TO THE SERUM PROTEINS.脑脊液中蛋白质成分的电泳研究及其与血清蛋白质的关系
J Clin Invest. 1942 Sep;21(5):571-7. doi: 10.1172/JCI101335.
3
[Radioactive sodium Na24 and cerebrospinal fluid; applications to the diagnosis of tuberculous meningitis and spinal cord compression].[放射性钠 Na24 与脑脊液；在结核性脑膜炎和脊髓压迫症诊断中的应用]
Rev Neurol (Paris). 1951 Jul;85(1):17-35.
4
THE DISTRIBUTION OF POTASSIUM, SODIUM, CHLORIDE AND UREA BETWEEN LUMBAR CEREBROSPINAL FLUID AND BLOOD SERUM IN HUMAN SUBJECTS.人体腰椎脑脊液与血清中钾、钠、氯及尿素的分布
Clin Sci. 1963 Aug;25:97-105.
5
The blood-C.S.F. barrier to bromide in diagnosis of tuberculous meningitis.
Lancet. 1954 Apr 3;266(6814):700-2. doi: 10.1016/s0140-6736(54)92108-x.
6
[Electrophoresis of pathological liquor cerebrospinalis].[病理性脑脊液的电泳]
Klin Wochenschr. 1953 Nov 1;31(41-42):969-75. doi: 10.1007/BF01533810.
7
Amino acid transport by choroid plexus in vitro.脉络丛在体外的氨基酸转运
J Neurochem. 1969 Apr;16(4):577-85. doi: 10.1111/j.1471-4159.1969.tb06857.x.
8
Free amino acids and related compounds in biopsies of human brain.
J Neurochem. 1971 Mar;18(3):521-8. doi: 10.1111/j.1471-4159.1971.tb11980.x.
9
Transfer of amino acids and urea to and from the subarachnoid space.
J Physiol. 1971 Oct;218 Suppl:42P-43P.
10
Spinal subarachnoid perfusion in the rat: glycine transport from spinal fluid.
J Neurochem. 1974 Mar;22(3):355-61. doi: 10.1111/j.1471-4159.1974.tb07600.x.