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病毒性和结核性脑膜炎患者脑脊液中的氨基酸浓度

Cerebrospinal fluid amino acid concentrations in patients with viral and tuberculous meningitis.

作者信息

Corston R N, McGale E H, Stonier C, Hutchinson E C, Aber G M

出版信息

J Neurol Neurosurg Psychiatry. 1981 Sep;44(9):791-5. doi: 10.1136/jnnp.44.9.791.

DOI:10.1136/jnnp.44.9.791
PMID:7310419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC491138/
Abstract

Serial measurements have been made of the cerebrospinal fluid and plasma amino acid concentrations in 11 patients with viral meningitis and in four with tuberculous meningitis. A small increase in the concentrations of a few amino acids in cerebrospinal fluid has been found in a viral meningitis in contrast to a marked increase in most amino acids in tuberculous meningitis. The findings are compared with those found in patients with purulent meningitis and the possible causes and the diagnostic significance of these findings are discussed.

摘要

对11例病毒性脑膜炎患者和4例结核性脑膜炎患者的脑脊液和血浆氨基酸浓度进行了系列测量。结果发现,病毒性脑膜炎患者脑脊液中少数几种氨基酸的浓度略有升高,而结核性脑膜炎患者多数氨基酸的浓度则显著升高。将这些结果与化脓性脑膜炎患者的结果进行了比较,并讨论了这些结果的可能原因及其诊断意义。

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本文引用的文献

1
Amino acid transport mechanisms of the cerebrospinal fluid.脑脊液的氨基酸转运机制。
Fed Proc. 1974 Sep;33(9):2079-85.
2
Free amino acids in the cerebrospinal fluid of epileptic subjects.
Epilepsia. 1974 Dec;15(4):593-7. doi: 10.1111/j.1528-1157.1974.tb04031.x.
3
Amino acid abnormalities in cerebrospinal fluid of patients with parkinsonism and extrapyramidal disorders.帕金森病和锥体外系疾病患者脑脊液中的氨基酸异常。
Neurology. 1976 May;26(5):489-93. doi: 10.1212/wnl.26.5.489.
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Studies of the inter-relationship between cerebrospinal fluid and plasma amino acid concentrations in normal individuals.
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Double-enzymatic assay for determination of glutamine and glutamic acid in cerebrospinal fluid and plasma.用于测定脑脊液和血浆中谷氨酰胺和谷氨酸的双酶法测定
Anal Chem. 1978 Jun;50(7):951-3. doi: 10.1021/ac50029a031.
6
Abnormalities of cerebrospinal fluid amino-acids in purulent meningitis.化脓性脑膜炎患者脑脊液氨基酸异常
J Neurol Neurosurg Psychiatry. 1979 Oct;42(10):881-6. doi: 10.1136/jnnp.42.10.881.
7
The effect of haemodialysis on cerebrospinal fluid and plasma amino acids.血液透析对脑脊液和血浆氨基酸的影响。
Clin Chim Acta. 1979 Feb 15;92(1):73-80. doi: 10.1016/0009-8981(79)90398-x.
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Studies of cerebrospinal fluid and plasma amino acids in patients with steady-state chronic renal failure.稳态慢性肾衰竭患者脑脊液和血浆氨基酸的研究。
Clin Chim Acta. 1979 Feb 15;92(1):65-72. doi: 10.1016/0009-8981(79)90397-8.