强直性肌营养不良症患者白细胞电泳迁移率异常。

Abnormal leukocyte electrophoretic mobility in myotonic dystrophy.

作者信息

Seay A R, Ziter F A, Hill H R

出版信息

J Neurol Sci. 1979 Dec;44(1):13-8. doi: 10.1016/0022-510x(79)90219-3.

Abstract

Electrophoretic mobility of polymorphonuclear leukocytes (PMNs) was studied in 10 patients with myotonic dystrophy. The mobility of patients' PMNs differed significantly from that of controls. Following incubation with bacterial chemotactic factor the PMNs from patients showed significantly less change in net surface charge compared to that in controls. Our data support a leukocyte membrane defect in myotonic dystrophy.

摘要

对10例强直性肌营养不良患者的多形核白细胞（PMNs）的电泳迁移率进行了研究。患者PMNs的迁移率与对照组有显著差异。与对照组相比，患者的PMNs在与细菌趋化因子孵育后，其净表面电荷的变化明显较小。我们的数据支持强直性肌营养不良存在白细胞膜缺陷。