Ohara I, Otsuka S I, Yugari Y
J Nutr. 1979 Dec;109(12):2098-105. doi: 10.1093/jn/109.12.2098.
The pancreatic secretory responses of dogs to various taste stimuli were examined in this study. Additionally, taste preferences were examined in 24-hour exposure tests to taste stimulus solutions as well as in short exposure tests to taste solutions mixed with commercial stock diet. The liquid and solid food preference tests produced quite different results. In dogs with cannulated gastric and duodenal fistulas, gustatory receptors were stimulated orally with 100 ml of taste stimulus solution (water 0.05 M monosodium glutamate (MSG), 0.05 M citric acid or 0.3 M sucrose) mixed with 25 g of a carrier (commercial stock diet, purified diet or cellulose). Pancreatic secretory responses to the taste stimuli varied with the type of carrier. Stock diet carrier was a better stimulant than the purified diet for both protein output and volume flow. Taste stimuli with a cellulose carrier did not produce any pancreatic response at all. The differences in responses to the different carriers were greater than the differences between taste stimuli when the same carrier was used. This experiment indicates that gustatory stimulation does influence the function of pancreatic secretion depending on the carriers used.
本研究检测了犬对各种味觉刺激的胰腺分泌反应。此外，在对味觉刺激溶液进行24小时暴露试验以及对与商业储备日粮混合的味觉溶液进行短期暴露试验中，检测了味觉偏好。液体和固体食物偏好试验产生了截然不同的结果。在具有插管胃瘘和十二指肠瘘的犬中，用100毫升与25克载体（商业储备日粮、纯化日粮或纤维素）混合的味觉刺激溶液（水、0.05M谷氨酸钠（MSG）、0.05M柠檬酸或0.3M蔗糖）经口刺激味觉感受器。胰腺对味觉刺激的分泌反应因载体类型而异。对于蛋白质输出量和体积流量而言，储备日粮载体比纯化日粮是更好的刺激物。含纤维素载体的味觉刺激根本不会产生任何胰腺反应。当使用相同载体时，对不同载体反应的差异大于味觉刺激之间的差异。该实验表明，味觉刺激确实会根据所用载体影响胰腺分泌功能。
