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1
Oxidation of nicotinic acid by a Bacillus species: purification and properties of nicotinic acid and 6-hydroxynicotinic acid hydroxylases.一种芽孢杆菌属细菌对烟酸的氧化作用：烟酸和6-羟基烟酸羟化酶的纯化及特性
J Bacteriol. 1971 Nov;108(2):751-6. doi: 10.1128/jb.108.2.751-756.1971.
2
Oxidation of nicotinic acid by a Bacillus species: source of oxygen atoms for the hydroxylation of nicotinic acid and 6-hydroxynicotinic acid.一种芽孢杆菌对烟酸的氧化作用：烟酸和6-羟基烟酸羟基化反应中氧原子的来源。
J Bacteriol. 1971 Nov;108(2):757-9. doi: 10.1128/jb.108.2.757-759.1971.
3
Oxidation of nicotinic acid by a Bacillus species: regulation of nicotinic acid and 6-hydroxynicotinic acid hydroxylases.一种芽孢杆菌属细菌对烟酸的氧化作用：烟酸和6-羟基烟酸羟化酶的调控
J Bacteriol. 1972 Oct;112(1):392-7. doi: 10.1128/jb.112.1.392-397.1972.
4
Nicotinic acid metabolism. 3. Purification and properties of a nicotinic acid hydroxylase.烟酸代谢。3. 一种烟酸羟化酶的纯化及特性
J Biol Chem. 1969 Mar 10;244(5):1194-203.
5
Glutamine synthetase of Bacillus stearothermophilus. I. Purification and basic properties.嗜热脂肪芽孢杆菌的谷氨酰胺合成酶。I. 纯化及基本性质。
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Purification and properties of an polygalacturonic acid trans-eliminase produced by Bacillus pumilus.短小芽孢杆菌产生的聚半乳糖醛酸反式消除酶的纯化及性质
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Purification and regulation of glucose-6-phosphate dehydrogenase from Bacillus licheniformis.地衣芽孢杆菌葡萄糖-6-磷酸脱氢酶的纯化与调控
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引用本文的文献

1
Microbial metabolism of pyridine, quinoline, acridine, and their derivatives under aerobic and anaerobic conditions.吡啶、喹啉、吖啶及其衍生物在有氧和无氧条件下的微生物代谢。
Microbiol Rev. 1996 Sep;60(3):483-98. doi: 10.1128/mr.60.3.483-498.1996.
2
Oxidation of nicotinic acid by a Bacillus species: source of oxygen atoms for the hydroxylation of nicotinic acid and 6-hydroxynicotinic acid.一种芽孢杆菌对烟酸的氧化作用：烟酸和6-羟基烟酸羟基化反应中氧原子的来源。
J Bacteriol. 1971 Nov;108(2):757-9. doi: 10.1128/jb.108.2.757-759.1971.
3
Oxidation of nicotinic acid by a Bacillus species: regulation of nicotinic acid and 6-hydroxynicotinic acid hydroxylases.一种芽孢杆菌属细菌对烟酸的氧化作用：烟酸和6-羟基烟酸羟化酶的调控
J Bacteriol. 1972 Oct;112(1):392-7. doi: 10.1128/jb.112.1.392-397.1972.
4
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Biochem J. 1972 Nov;130(1):121-32. doi: 10.1042/bj1300121.
5
Microbial metabolism of the pyridine ring. The hydroxylation of 4-hydroxypyridine to pyridine-3,4-diol (3,4-dihydroxypyridine) by 4-hydroxypyridine-3-hydroxylase.吡啶环的微生物代谢。4-羟基吡啶-3-羟化酶将4-羟基吡啶羟基化为吡啶-3,4-二醇（3,4-二羟基吡啶）。
Biochem J. 1974 May;140(2):265-76. doi: 10.1042/bj1400265.
6
Identification of cyclic intermediates in Azorhizobium caulinodans nicotinate catabolism.菜豆根瘤菌烟酸分解代谢中环状中间体的鉴定
J Bacteriol. 1989 Jun;171(6):3406-11. doi: 10.1128/jb.171.6.3406-3411.1989.
7
Elucidation of the complete Azorhizobium nicotinate catabolism pathway.解明烟碱酸完全分解代谢途径。
J Bacteriol. 1992 Dec;174(23):7791-7. doi: 10.1128/jb.174.23.7791-7797.1992.
8
Fermentative degradation of dipicolinic acid (pyridine-2,6-dicarboxylic acid) by a defined coculture of strictly anaerobic bacteria.由严格厌氧细菌的特定共培养物对二吡啶甲酸（吡啶-2,6-二羧酸）进行发酵降解。
Biodegradation. 1990;1(1):1-7. doi: 10.1007/BF00117046.
9
Degradation of 3-hydroxybenzoate by bacteria of the genus Bacillus.芽孢杆菌属细菌对3-羟基苯甲酸的降解作用。
Appl Microbiol. 1975 Sep;30(3):439-44. doi: 10.1128/am.30.3.439-444.1975.

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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6-Hydroxynicotinic acid as an intermediate in the oxidation of nicotinic acid by Pseudomonas fluorescens.6-羟基烟酸作为荧光假单胞菌氧化烟酸过程中的一种中间体。
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DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.圆盘电泳。II. 方法及其在人血清蛋白中的应用。
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THE PATHWAY OF NICOTINIC ACID OXIDATION BY A BACILLUS SPECIES.一种芽孢杆菌属细菌氧化烟酸的途径。
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NICOTINIC ACID METABOLISM. I. DISTRIBUTION OF ISOTOPE IN FERMENTATION PRODUCTS OF LABELLED NICOTINIC ACID.烟酸代谢。一、标记烟酸发酵产物中同位素的分布
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alpha-Keto acid dehydrogenation complexes. IV. Resolution and reconstitution of the Escherichia coli pyruvate dehydrogenation complex.α-酮酸脱氢酶复合体。IV. 大肠杆菌丙酮酸脱氢酶复合体的拆分与重组。
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Simplified methods for the estimation of iron in mitochondria and submitochondrial fractions.线粒体和亚线粒体组分中铁含量估算的简化方法。
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Purification of the nicotinic acid hydroxylase system of Pseudomonas fluorescens KB1.荧光假单胞菌KB1烟酸酸羟化酶系统的纯化
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The bacterial oxidation of nicotinic acid.烟酸的细菌氧化作用。
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Bacterial fermantation of nicotinic acid. II. Anaerobic reversible hydroxylation of nicotinic acid to 6-hydroxynicotinic acid.烟酸的细菌发酵。II. 烟酸厌氧可逆羟基化为6-羟基烟酸。
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一种芽孢杆菌属细菌对烟酸的氧化作用：烟酸和6-羟基烟酸羟化酶的纯化及特性

Oxidation of nicotinic acid by a Bacillus species: purification and properties of nicotinic acid and 6-hydroxynicotinic acid hydroxylases.

作者信息

Hirschberg R, Ensign J C

出版信息

J Bacteriol. 1971 Nov;108(2):751-6. doi: 10.1128/jb.108.2.751-756.1971.

DOI:10.1128/jb.108.2.751-756.1971
PMID:5128334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC247135/
Abstract

The enzymes of a Bacillus species that hydroxylate nicotinic acid to 6-hydroxynicotinic acid and 6-hydroxynicotinic acid to 2,6-dihydroxynicotinic acid were purified and characterized. The purified enzymes contained approximately two molecules of flavine and eight molecules of iron per molecule of enzyme. The enzymes were large (molecular weight, 400,000 to 450,000) and appeared to consist of subunits.

摘要

一种芽孢杆菌属的将烟酸羟基化为6-羟基烟酸以及将6-羟基烟酸羟基化为2,6-二羟基烟酸的酶被纯化并进行了特性鉴定。纯化后的酶每分子酶含有约两个黄素分子和八个铁分子。这些酶很大（分子量为400,000至450,000），似乎由亚基组成。