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两种外周血管扩张剂盐酸尼立替林和盐酸异克舒令在药物剂型中的高效液相色谱法

High-performance liquid chromatography of two peripheral vasodilators, nylidrin hydrochloride and isoxsuprine hydrochloride, in pharmaceutical dosage forms.

作者信息

Volpe F, Zintel J, Spiegel D

出版信息

J Pharm Sci. 1979 Oct;68(10):1264-7. doi: 10.1002/jps.2600681018.

DOI:10.1002/jps.2600681018
PMID:512857
Abstract

A reliable and selective high-pressure liquid chromatographic (HPLC) procedure for the quantitative determination of nylidrin hydrochloride or isoxsuprine hydrochloride in pharmaceutical dosage forms is described. The specificity of the stability-indicating HPLC procedure is presented for nylidrin hydrochloride.

摘要

本文描述了一种可靠且具选择性的高效液相色谱(HPLC)方法,用于定量测定药物剂型中的盐酸尼立替林或盐酸异克舒令。本文还展示了该稳定性指示HPLC方法对盐酸尼立替林的专属性。

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