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母婴血液叶酸活性之间的关系。

Relation between maternal and infant blood folate activities.

作者信息

Landon M J, Oxley A

出版信息

Arch Dis Child. 1971 Dec;46(250):810-4. doi: 10.1136/adc.46.250.810.

Abstract

The relation between maternal and cord blood folate activity was investigated in a group of 110 primigravidae and their infants. Approximately half of these mothers had received folic acid supplements during their pregnancy, and the effects of this on infant blood folate levels at birth and at 6 weeks were also studied. In unsupplemented pregnancies there was a significant relation between infant and maternal blood folate levels at delivery. The results of folic acid supplementation during pregnancy were reflected by higher cord blood values, but 6 weeks after delivery infant plasma folate levels were the same in both groups and independent of maternal supplies before delivery.

摘要

对110名初产妇及其婴儿组成的群体进行了母体和脐带血叶酸活性之间关系的研究。这些母亲中约有一半在孕期接受了叶酸补充剂,同时也研究了这对婴儿出生时及6周时血液叶酸水平的影响。在未补充叶酸的妊娠中,分娩时婴儿和母体血液叶酸水平之间存在显著关系。孕期补充叶酸的结果表现为脐带血值较高,但分娩后6周,两组婴儿血浆叶酸水平相同,且与分娩前母体的叶酸供给无关。

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本文引用的文献

1
MEGALOBLASTIC ANAEMIA IN PREMATURE INFANTS.早产儿巨幼细胞贫血
Arch Dis Child. 1965 Feb;40(209):53-6. doi: 10.1136/adc.40.209.53.
5
FOLIC ACID DEFICIENCY AND PREMATURITY.叶酸缺乏与早产
J Pediatr. 1964 Mar;64:323-9. doi: 10.1016/s0022-3476(64)80184-0.
6
THE RENAL EXCRETION OF FOLIC ACID.叶酸的肾脏排泄
J Clin Invest. 1963 Dec;42(12):1841-9. doi: 10.1172/JCI104868.
7
Blood folic acid and vitamin B12 activities in healthy infants and in infants with nutritional anaemias.
Br J Haematol. 1963 Jul;9:328-35. doi: 10.1111/j.1365-2141.1963.tb06557.x.
8
Pantothenic acid, thiamine and folic acid levels at parturition.分娩时泛酸、硫胺素和叶酸水平。
Proc Soc Exp Biol Med. 1960 Feb;103:321-3. doi: 10.3181/00379727-103-25504.
9
Folic and folinic acid in maternal and foetal blood.母体和胎儿血液中的叶酸和亚叶酸
Br J Haematol. 1960 Jul;6:296-302. doi: 10.1111/j.1365-2141.1960.tb06246.x.

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