在弗氏佐剂中注射大鼠肾上腺的大鼠引流腘淋巴结中细胞群体的生长情况。
The growth of the cell population in the draining popliteal lymph node of rats injected with rat adrenal in Freund's Adjuvant.
作者信息
Werdelin O, Foley P S, Rose N R, McCluskey R T
出版信息
Immunology. 1971 Dec;21(6):1059-63.
The growth of the cell population and the rate of cell proliferation in the draining popliteal lymph node was studied in rats injected in the foot with adrenal tissue antigen-adjuvant emulsion and pertussis vaccine. The number of cells in the lymph node quadrupled during the first two days after injection prior to any significant increase in the rate of cell proliferation as measured by the number of cells incorporating H-thymidine . After the second day proliferation of cells contributed to the growth of the lymph node's cell population. It is suggested that the early sudden growth of the cell population is brought about partly by an increase in the influx of lymphocytes from the blood into the lymph node and partly by a decrease in the efflux of lymphocytes with the efferent lymph from the lymph node.
在给大鼠足部注射肾上腺组织抗原-佐剂乳剂和百日咳疫苗后，研究了引流腘淋巴结中细胞群体的生长和细胞增殖速率。在注射后的前两天，淋巴结中的细胞数量增加了四倍，而在此之前，通过掺入³H-胸腺嘧啶核苷的细胞数量所测量的细胞增殖速率并没有显著增加。第二天之后，细胞增殖对淋巴结细胞群体的生长起到了促进作用。有人提出，细胞群体的早期突然增长部分是由于从血液进入淋巴结的淋巴细胞流入增加，部分是由于从淋巴结通过输出淋巴管流出的淋巴细胞减少。
Zotero 插件