Kalden J R, James K
Immunology. 1971 Mar;20(3):269-75.
Anti-lymphocytic IgG given immediately after the injection of thyroglobulin in Freund's complete adjuvant suppressed the development of cellular and humoral immune reactions to thyroglobulin in rats immunized into a hind footpad but failed to exert a significant effect when the antigen was injected into two cervical lymph nodes. However, treatment with anti-lymphocytic IgG for 3 days prior to intra-lymph node immunization with thyroglobulin prevented the development of cellular and humoral immune responses to this antigen.
在弗氏完全佐剂中注射甲状腺球蛋白后立即给予抗淋巴细胞IgG,可抑制在大鼠后足垫免疫的大鼠对甲状腺球蛋白的细胞免疫和体液免疫反应的发展,但当抗原注射到两个颈淋巴结时,该抗体未能发挥显著作用。然而,在用甲状腺球蛋白进行淋巴结内免疫前3天用抗淋巴细胞IgG治疗,可阻止对该抗原的细胞免疫和体液免疫反应的发展。