磷脂酰胆碱囊泡对DNA聚合酶α活性的影响。
Effect of phosphatidylcholine vesicles on the activity of DNA polymerase-alpha.
作者信息
Capitani S, Mazzotti G, Jovine R, Papa S, Maraldi N M, Manzoli F A
出版信息
Mol Cell Biochem. 1979 Nov 1;27(3):135-8. doi: 10.1007/BF00215361.
PMID:514266
Abstract
Phosphatidylcholine vesicles stimulate the activity of the DNA polymerase-alpha from calf thymus. This effect is dependent upon the way of addition to the Mg ions, and the extent of the 3H-dTTP incorporation is closely related to the concentration of the vesicles. A role of phospholipids on the activity of the DNA-related enzymes is suggested.
摘要
磷脂酰胆碱囊泡可刺激来自小牛胸腺的DNA聚合酶α的活性。这种效应取决于添加镁离子的方式，并且3H-dTTP掺入的程度与囊泡的浓度密切相关。这表明磷脂在与DNA相关的酶的活性中发挥作用。
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