肌醇六磷酸掺入完整红细胞。I. 含效应物的脂质囊泡与红细胞的融合。
Incorporation of inositol hexaphosphate into intact red blood cells. I. Fusion of effector-containing lipid vesicles with erythrocytes.
作者信息
Nicolau C, Gersonde K
出版信息
Naturwissenschaften. 1979 Nov;66(11):563-6. doi: 10.1007/BF00368810.
PMID:514370
Abstract
Fluid charged lipid vesicles loaded with an inositol hexaphosphate solution were used to transport this allosteric effector into human intact red blood cells. Rate and extent of uptake of the vesicles and of the effector by the red blood cells were measured as changes in the O2 half-saturation pressure and the 31P-NMR spectra of the intracellular inositol hexaphosphate-haemoglobin complex.
摘要
装载有肌醇六磷酸溶液的带电荷脂质囊泡被用于将这种变构效应剂转运到人类完整红细胞中。通过测量细胞内肌醇六磷酸 - 血红蛋白复合物的氧气半饱和压力和31P - NMR谱的变化，来测定红细胞对囊泡和效应剂的摄取速率及摄取程度。
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