胸苷酸合成酶。5-三氟甲基-2'-脱氧尿苷酸抑制作用的模型研究。 - Suppr

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Thymidylate synthetase. Model studies of inhibition by 5-trifluoromethyl-2'-deoxyuridylic acid.

作者信息

Santi D V, Sakai T T

出版信息

Biochemistry. 1971 Sep 14;10(19):3598-607. doi: 10.1021/bi00795a018.

DOI:10.1021/bi00795a018

PMID:5146573

Abstract

摘要

相似文献

Thymidylate synthetase. Model studies of inhibition by 5-trifluoromethyl-2'-deoxyuridylic acid.胸苷酸合成酶。5-三氟甲基-2'-脱氧尿苷酸抑制作用的模型研究。

Biochemistry. 1971 Sep 14;10(19):3598-607. doi: 10.1021/bi00795a018.

Irreversible inhibition of thymidylate synthetase by 5-formyl-2'-deoxyuridylic acid.5-甲酰基-2'-脱氧尿苷酸对胸苷酸合成酶的不可逆抑制作用。

Biochem Biophys Res Commun. 1972 Feb 16;46(3):1320-5. doi: 10.1016/s0006-291x(72)80119-0.

5-Fluoro-2'-deoxyuridylate: covalent complex with thymidylate synthetase.5-氟-2'-脱氧尿苷酸：与胸苷酸合成酶的共价复合物。

Proc Natl Acad Sci U S A. 1972 Jul;69(7):1855-7. doi: 10.1073/pnas.69.7.1855.

Poly 2'-deoxy-2'-aminouridylic acid.聚2'-脱氧-2'-氨基尿苷酸

Biochem Biophys Res Commun. 1972 Feb 25;46(4):1509-15. doi: 10.1016/0006-291x(72)90778-4.

Inhibition of thymidylate synthetase by 5-formyl- and 5-hydroxymethyl-2'-deoxyuridylate.5-甲酰基-2'-脱氧尿苷酸和5-羟甲基-2'-脱氧尿苷酸对胸苷酸合成酶的抑制作用

Biochem Biophys Res Commun. 1971 Mar 5;42(5):813-7. doi: 10.1016/0006-291x(71)90502-x.

Methylation of 4-thio-2'-deoxyuridylate by thymidylate synthetase.胸苷酸合成酶对4-硫代-2'-脱氧尿苷酸的甲基化作用。

Biochem Biophys Res Commun. 1973 Nov 1;55(1):210-7. doi: 10.1016/s0006-291x(73)80081-6.

Model studies of thymidylate synthetase. Intramolecular catalysis of 5-hydrogen exchange and 5-hydroxymethylation of 1-substituted uracils.

Biochemistry. 1973 Jun 19;12(13):2416-24. doi: 10.1021/bi00737a008.

A novel procedure for the synthesis of 2'-O-alkyl nucleotides.一种合成2'-O-烷基核苷酸的新方法。

Biochemistry. 1972 Dec 19;11(26):4931-7. doi: 10.1021/bi00776a009.

Inhibition of inosinic acid dehydrogenase of sarcoma 180 ascites cells by nucleotides and their analogs.核苷酸及其类似物对肉瘤180腹水癌细胞肌苷酸脱氢酶的抑制作用。

Biochem Pharmacol. 1969 Oct;18(10):2747-57. doi: 10.1016/0006-2952(69)90182-8.

Alkylation of cytosine glycosides in alkaline medium: a new route to the preparation of O'-alkylated nucleosides and nucleotides of cytosine and uracil.碱性介质中胞嘧啶糖苷的烷基化：制备胞嘧啶和尿嘧啶的O'-烷基化核苷及核苷酸的新途径。

Acta Biochim Pol. 1971;18(4):413-8.

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