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视觉皮层超同步爆发作为行为状态转变的一个指标。

Visual cortical hypersynchronous bursting as an index of shifts in behavioral state.

作者信息

Standage G P, Fleming D E

出版信息

Physiol Behav. 1979 Jul;23(1):35-8. doi: 10.1016/0031-9384(79)90119-7.

DOI:10.1016/0031-9384(79)90119-7
PMID:515215
Abstract

Photically evoked after-discharge (PhAD) bursting was examined in lightly restrained albino rats during habituation of a leg flexion response. The initial effect of iterative footshock (200 trials, 0.17 mA, 2.5 msec duration, separated by 1.0 sec) was to block PhAD bursting. As response habituation developed PhAD reappeared at reduced levels, subsequently returning to control levels as habituation progressed and became complete. The number of spindles per PhAD burst was suppressed for a brief period which coincided with response sensitization. These results are interpreted as demonstrating that phasic shifts in behavioral state are reflected by PhAD parameters. In addition, the possible relationship between cortical information processing and PhAD bursting is discussed with reference to putative neural mechanisms involved.

摘要

在轻度束缚的白化大鼠腿部屈曲反应习惯化过程中,研究了光诱发后放电(PhAD)爆发。反复足部电击(200次试验,0.17 mA,持续2.5毫秒,间隔1.0秒)的初始效应是阻断PhAD爆发。随着反应习惯化的发展,PhAD在较低水平重新出现,随后随着习惯化的进展并完成而恢复到对照水平。每个PhAD爆发的纺锤体数量在与反应敏感化同时发生的短时间内受到抑制。这些结果被解释为表明行为状态的相位变化由PhAD参数反映。此外,还参考所涉及的假定神经机制讨论了皮质信息处理与PhAD爆发之间的可能关系。

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