Varma P K, Persaud T V
Res Commun Chem Pathol Pharmacol. 1979 Oct;26(1):65-73.
Pyrazole, a potent inhibitor of alcohol dehydrogenase, induced a high incidence of ocular and urinary bladder anomalies in the offspring of rats following treatment on gestational day 9. A single moderate dose of ethanol potentiated the teratogenic action of pyrazole, but alone did not affect embryonic development.
吡唑是一种有效的乙醇脱氢酶抑制剂，在妊娠第9天对大鼠进行治疗后，其后代出现眼部和膀胱异常的发生率很高。单次中等剂量的乙醇可增强吡唑的致畸作用，但单独使用乙醇不会影响胚胎发育。
