Strauss M E, Bohannon W E, Kaminsky M J, Kharabi F
Schizophr Bull. 1979;5(4):612-5. doi: 10.1093/schbul/5.4.612.
A crossover pattern similar to that reported for inpatient schizophrenics (e.g., Bellissimo and Steffy 1972) has now been found for outpatients, and its frequency of occurrence in these outpatients is comparable to that reported for hospitalized patients by DeAmicas and Cromwell (1978). The process-reactive construct was unrelated to crossover in the current study, although crossover is found only in process patients in hospitalized samples. The difference in findings may be due to the insensitivity of the particular measure of this concept used here, or to the lack of validity for the construct in samples of chronic patients in the community and in treatment. The present results, together with DeAmicas and Cromwell's (1978) data suggestive of the presence of crossover in nondisturbed first degree relatives of schizophrenics, are consistent with an interpretation of this reaction time phenomenon as a behavioral marker of vulnerability. This hypothesis warrants study in a more extensive series of patients, and from a longitudinal perspective in which behavioral measures and clinical-social functioning variables are tracked across time.
现在已发现门诊精神分裂症患者呈现出一种与住院精神分裂症患者报告中类似的交叉模式（例如，贝利西莫和斯特菲，1972年），并且这种交叉模式在这些门诊患者中的出现频率与德阿米卡斯和克伦威尔（1978年）报告的住院患者的频率相当。在当前研究中，过程-反应性结构与交叉现象无关，尽管在住院样本中仅在过程患者中发现了交叉现象。研究结果的差异可能是由于此处使用的该概念的特定测量方法不敏感，或者是由于该结构在社区慢性病患者样本和治疗中缺乏有效性。目前的结果，连同德阿米卡斯和克伦威尔（1978年）的数据表明精神分裂症未受干扰的一级亲属中存在交叉现象，这与将这种反应时间现象解释为易感性的行为标志物是一致的。这一假设值得在更广泛的患者系列中进行研究，并从纵向角度进行研究，即随时间跟踪行为测量和临床-社会功能变量。
