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反应时交叉作为精神分裂症及高功能的一个标志物。

Reaction time crossover as a marker of schizophrenia and of higher functioning.

作者信息

De Amicis L A, Wagstaff D A, Cromwell R L

出版信息

J Nerv Ment Dis. 1986 Mar;174(3):177-9. doi: 10.1097/00005053-198603000-00010.

DOI:10.1097/00005053-198603000-00010
PMID:3950602
Abstract

A factor analysis of reaction time crossover data of 53 schizophrenic patients, 45 first-degree relatives, and 38 controls, previously reported by De Amicis and Cromwell, was performed in order to shed light upon the relationship of crossover to aging, mean reaction time, and general socioeconomic functioning. The aging factor shared variance with getting married and having children, but not with reaction time crossover. Crossover was also found to be independent of reaction time speed among first-degree relatives and control subjects; however, it was correlated with reaction time speed among actively symptomatic schizophrenic patients. Additionally, the relationship of crossover to socioeconomic functioning was found to be negative among the patients, positive among the relatives, and nonexistent among control subjects. Results are discussed in terms of previous reports of higher than normal functioning found in relatives of schizophrenic patients.

摘要

对先前由德阿米西斯和克伦威尔报告的53名精神分裂症患者、45名一级亲属和38名对照者的反应时间交叉数据进行了因子分析,以便阐明交叉与衰老、平均反应时间和一般社会经济功能之间的关系。衰老因子与结婚和生育共享方差,但与反应时间交叉无关。在一级亲属和对照者中,交叉也被发现与反应时间速度无关;然而,在有明显症状的精神分裂症患者中,交叉与反应时间速度相关。此外,发现交叉与社会经济功能的关系在患者中为负,在亲属中为正,在对照者中不存在。根据先前关于精神分裂症患者亲属中发现高于正常功能的报告对结果进行了讨论。

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Reaction time crossover as a marker of schizophrenia and of higher functioning.反应时交叉作为精神分裂症及高功能的一个标志物。
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Simple reaction time crossover occurs in schizophrenic outpatients.简单反应时交叉现象出现在精神分裂症门诊患者中。
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Sustained attention deficit and schizotypal personality features in nonpsychotic relatives of schizophrenic patients.精神分裂症患者非精神病性亲属的持续性注意力缺陷和分裂样人格特征。
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Reaction time crossover in process schizophrenic patients, their relatives, and control subjects.过程性精神分裂症患者、其亲属及对照受试者的反应时交叉现象。
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Magnitude of reaction time crossover in process schizophrenic patients in relation to their first-degree relatives.精神分裂症患者与其一级亲属在病程中反应时间交叉的程度。
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The executive control of attention differentiates patients with schizophrenia, their first-degree relatives and healthy controls.注意的执行控制区分了精神分裂症患者、他们的一级亲属和健康对照者。
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Reaction time of the Continuous Performance Test is an endophenotypic marker for schizophrenia: a study of first-episode neuroleptic-naive schizophrenia, their non-psychotic first-degree relatives and healthy population controls.持续性操作测试的反应时间是精神分裂症的一种内表型标记:一项针对首发未使用抗精神病药物的精神分裂症患者、其非精神病性一级亲属和健康人群对照的研究。
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Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus.精神分裂症的一种神经生理缺陷与15号染色体位点的连锁关系。
Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):587-92. doi: 10.1073/pnas.94.2.587.