Suppr超能文献

[兔子器官和组织的磷脂组成]

[The phospholipid composition of organs and tissues of rabbit].

作者信息

Kostetskii E Ia, Gerasimenko N I, Kushnerova N F

出版信息

Biokhimiia. 1977 Apr;42(4):672-6.

PMID:870088
Abstract

The phospholipid compositions of 11 organs and tissues of rabbit (brain, heart, lung, liver, muscles, kidney, spleen, bone marrow, pancreas, adrenula, and blood plasma) were comparatively studied by micro-thin-layer chromatography. Total lipid extracts of liver and brain are the most abundant in phospholipid (61,8% and 56,3%, respectively) and that of bone marrow and spleen are the poorest (1,6% and 7,1%, respectively). All the organs and tissues, except blood plasma, contain phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, phosphatidylinositol, sphingomyelin and diphosphatidylglicerol; the majority of organs contain phosphatidic acid. Lyso-phosphatidyl-choline was detected in blood plasma, bone marrow, adrenula and liver. Phosphatidylglicerol was found only in the lungs. Brain has the lowest content of phosphatidyl choline (34,3%) and the highest contents of phosphatidyl ethanolamine (36,2%) and phosphatidyl serine (12,6%), whereas the heart is the richest in DPG (about 11%). Diphosphatidyl glycerol is the most abundant in the heart (approximately 11%) and phosphatidyl inositol-- in the adrenula (8,1%). Plasma is found to have a high content of choline-containing lipids; however, phosphatidyl serine and phosphatidic acid are absent altogether. Some of the organs and tissues have a similar phospholipid composition; namely brain and kidney, spleen and bone marrow, adrenula and liver.

摘要

采用微量薄层色谱法对家兔的11种器官和组织(脑、心脏、肺、肝脏、肌肉、肾脏、脾脏、骨髓、胰腺、肾上腺和血浆)的磷脂组成进行了比较研究。肝脏和脑的总脂质提取物中磷脂含量最为丰富(分别为61.8%和56.3%),而骨髓和脾脏的磷脂含量则最低(分别为1.6%和7.1%)。除血浆外,所有器官和组织均含有磷脂酰胆碱、磷脂酰乙醇胺、磷脂酰丝氨酸、磷脂酰肌醇、鞘磷脂和二磷脂酰甘油;大多数器官含有磷脂酸。在血浆、骨髓、肾上腺和肝脏中检测到溶血磷脂酰胆碱。仅在肺中发现磷脂酰甘油。脑中磷脂酰胆碱含量最低(34.3%),磷脂酰乙醇胺(36.2%)和磷脂酰丝氨酸(12.6%)含量最高,而心脏中双磷脂酰甘油含量最丰富(约11%)。双磷脂酰甘油在心脏中含量最高(约11%),磷脂酰肌醇在肾上腺中含量最高(8.1%)。发现血浆中含胆碱脂质的含量较高;然而,完全不存在磷脂酰丝氨酸和磷脂酸。一些器官和组织具有相似的磷脂组成;即脑和肾、脾和骨髓、肾上腺和肝脏。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验