Kostetskii E Ia, Gerasimenko N I, Kushnerova N F
Biokhimiia. 1977 Apr;42(4):672-6.
The phospholipid compositions of 11 organs and tissues of rabbit (brain, heart, lung, liver, muscles, kidney, spleen, bone marrow, pancreas, adrenula, and blood plasma) were comparatively studied by micro-thin-layer chromatography. Total lipid extracts of liver and brain are the most abundant in phospholipid (61,8% and 56,3%, respectively) and that of bone marrow and spleen are the poorest (1,6% and 7,1%, respectively). All the organs and tissues, except blood plasma, contain phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, phosphatidylinositol, sphingomyelin and diphosphatidylglicerol; the majority of organs contain phosphatidic acid. Lyso-phosphatidyl-choline was detected in blood plasma, bone marrow, adrenula and liver. Phosphatidylglicerol was found only in the lungs. Brain has the lowest content of phosphatidyl choline (34,3%) and the highest contents of phosphatidyl ethanolamine (36,2%) and phosphatidyl serine (12,6%), whereas the heart is the richest in DPG (about 11%). Diphosphatidyl glycerol is the most abundant in the heart (approximately 11%) and phosphatidyl inositol-- in the adrenula (8,1%). Plasma is found to have a high content of choline-containing lipids; however, phosphatidyl serine and phosphatidic acid are absent altogether. Some of the organs and tissues have a similar phospholipid composition; namely brain and kidney, spleen and bone marrow, adrenula and liver.
采用微量薄层色谱法对家兔的11种器官和组织(脑、心脏、肺、肝脏、肌肉、肾脏、脾脏、骨髓、胰腺、肾上腺和血浆)的磷脂组成进行了比较研究。肝脏和脑的总脂质提取物中磷脂含量最为丰富(分别为61.8%和56.3%),而骨髓和脾脏的磷脂含量则最低(分别为1.6%和7.1%)。除血浆外,所有器官和组织均含有磷脂酰胆碱、磷脂酰乙醇胺、磷脂酰丝氨酸、磷脂酰肌醇、鞘磷脂和二磷脂酰甘油;大多数器官含有磷脂酸。在血浆、骨髓、肾上腺和肝脏中检测到溶血磷脂酰胆碱。仅在肺中发现磷脂酰甘油。脑中磷脂酰胆碱含量最低(34.3%),磷脂酰乙醇胺(36.2%)和磷脂酰丝氨酸(12.6%)含量最高,而心脏中双磷脂酰甘油含量最丰富(约11%)。双磷脂酰甘油在心脏中含量最高(约11%),磷脂酰肌醇在肾上腺中含量最高(8.1%)。发现血浆中含胆碱脂质的含量较高;然而,完全不存在磷脂酰丝氨酸和磷脂酸。一些器官和组织具有相似的磷脂组成;即脑和肾、脾和骨髓、肾上腺和肝脏。