Mehta P P, Sagar S, Kakkar V V
Br Med J. 1975 Sep 13;3(5984):614-6. doi: 10.1136/bmj.3.5984.614.
In a prospective, double-blind, randomized trial the efficacy of a heparinoid in ointment form was assessed in treating superficial thrombophlebitis developing after continuous intravenous infusion. One hundred surgical patients were studied, and clinical examination and the iodine-125-labelled fibrinogen test used to assess the results. The mean time required for the relief of local symptoms and signs and the rate of local decline in radioactivity differed significantly between patients receiving the heparinoid cream and those recieving the placebo.
在一项前瞻性、双盲、随机试验中,评估了一种软膏剂型类肝素在治疗连续静脉输注后发生的浅表血栓性静脉炎方面的疗效。研究了100例外科手术患者,并通过临床检查和碘-125标记的纤维蛋白原试验来评估结果。接受类肝素乳膏的患者与接受安慰剂的患者在缓解局部症状和体征所需的平均时间以及局部放射性下降率方面存在显著差异。