Minev M, Martinova F, Dinev D, Dimitrova D
Vutr Boles. 1979;18(5):48-53.
With the investigation of HL A phenotypes of 133 patients with an akylozing spondylarthritis, 110 males and 23 females, confirmed incidence of antigen B 27 was established in 87.96 per cent versus 10.78 per cent of 1085 control healthy subjects. The families of 24 patients were also examined with a total of 27 subjects HLA-B27 positive relations, among them 11 cases of SA with a latent course so far. The results from those exminations reveal that HLA-B27 antigen investigations could aid making the diagnosis in cases, suspected of SA, together with the other diagnostic methods.
对133例强直性脊柱炎患者(110例男性,23例女性)的HLA表型进行调查,确诊抗原B27的发生率为87.96%,而1085名健康对照者的发生率为10.78%。还对24例患者的家族进行了检查,共有27名受试者HLA - B27呈阳性关系,其中11例迄今为隐匿性病程的强直性脊柱炎。这些检查结果表明,HLA - B27抗原检测与其他诊断方法一起,有助于对疑似强直性脊柱炎的病例进行诊断。