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[民主德国的卡介苗接种——回顾与展望(作者译)]

[BCG-vaccination in the GDR--retrospective and prospective view (author's transl)].

作者信息

Landmann H

出版信息

Z Erkr Atmungsorgane. 1979 Apr;153(1):50-9.

PMID:516803
Abstract

A retrospective evaluation of BCG-vaccination from 1951--1977 shows the good effect on the number of TB-diseases especially among children. In former years with an annually infection-risk of 6--10% we found a big difference between TB-diseases in vaccinated and non-vaccinated persons. With the decreasing infections-risk (1977 0,05%) the absolute number and difference of diseases in vaccinated and non-vaccinated have become smaller and smaller. Nevertheless the decision was made to continue the BCG-vaccination of new-borns and pupils of 16 years in order to avoid also the last few cases of TB in children. The used BCG-vaccine produced in Jena/DDR has proved its immunogenic effect and caused very few complications. Till 1977 among nearly 10 millions of vaccinations only 68, mostly slight complications were registered.

摘要

对1951年至1977年卡介苗接种情况的回顾性评估显示,其对结核病发病数量有良好效果,尤其是在儿童中。在过去每年感染风险为6%至10%的年份里,我们发现接种疫苗者和未接种疫苗者的结核病发病情况存在很大差异。随着感染风险降低(1977年为0.05%),接种疫苗者和未接种疫苗者的疾病绝对数量及差异越来越小。尽管如此,仍决定继续对新生儿和16岁的学生进行卡介苗接种,以避免儿童中最后几例结核病病例。在东德耶拿生产的卡介苗已证明其免疫原性效果,且引起的并发症极少。到1977年,在近1000万次接种中,仅记录到68例并发症,大多为轻微并发症。

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