Salyer D C, Salyer W R, Eggleston J C
Cancer. 1975 Oct;36(4):1522-37. doi: 10.1002/1097-0142(197510)36:4<1522::aid-cncr2820360447>3.0.co;2-y.
Twenty-eight pulmonary carcinoid tumors were reviewed histologically and clinically. Hematoxylin-and-eosin-stained sections were utilized, as well as special stains, including the argyrophil and argentaffin reactions. The 22 tumors located centrally, at the level of primary or segmental bronchi, had a microscopic appearance distinct from those located more peripherally. One peripheral tumor that was large in size appeared much more aggressive histologically, and was designated an atypical carcinoid. The origin of carcinoid tumors from Kulchitsky cells in the lung, the distinction of peripheral tumors from chemodectomas, and the relationship of bronchial carcinoids to bronchial epithelial hyperplasias and oat cell carcinomas are discussed.
对28例肺类癌肿瘤进行了组织学和临床检查。使用苏木精-伊红染色切片以及特殊染色,包括嗜银和亲银反应。位于中央、主支气管或段支气管水平的22个肿瘤,其显微镜下表现与位于更外周的肿瘤不同。一个体积较大的外周肿瘤在组织学上表现出更强的侵袭性,被定为非典型类癌。讨论了肺类癌肿瘤起源于肺内的库尔契茨基细胞、外周肿瘤与化学感受器瘤的区别,以及支气管类癌与支气管上皮增生和燕麦细胞癌的关系。