绒毛膜类型对单卵双胞胎脐血胆固醇变化的影响。
Effects of chorion type on variation in cord blood cholesterol of monozygotic twins.
作者信息
Corey L A, Kang K W, Christian J C, Norton J A, Harris R E, Nance W E
出版信息
Am J Hum Genet. 1976 Sep;28(5):433-41.
Abstract
Cholesterol levels were measured in the cord blood of 30 pairs of monochorionic and 22 pairs of dichorionic monozygotic (MZ) twins. Cholesterol levels were found to be significantly higher in female twins when data was combined over chorion type. The type of chorionic development had no significant effect on variation among twin pairs. Chorion type did, however, have a significant effect on the within-pair variation. The variation within dichorionic pairs was more than five times that within monochorionic pairs (P less than .01). This result suggests that the variation in placentation has a significant effect on within-pair variation in serum cholesterol of newborn MZ twins.
摘要
在30对单绒毛膜和22对双绒毛膜单卵双胎（MZ）双胞胎的脐血中测量了胆固醇水平。当按绒毛膜类型合并数据时，发现女性双胞胎的胆固醇水平显著更高。绒毛膜发育类型对双胞胎对之间的差异没有显著影响。然而，绒毛膜类型对双胞胎对内差异有显著影响。双绒毛膜双胞胎对之间的差异是单绒毛膜双胞胎对之间差异的五倍多（P小于0.01）。这一结果表明，胎盘形成的差异对新生MZ双胞胎血清胆固醇的双胞胎对内差异有显著影响。
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