膜结合免疫球蛋白决定簇的证实以及所用抗血清定量表征的意义。
Demonstration of membrane-bound immunoglobulin determinants and the significance of a quantitative characterization of the antisera used.
作者信息
Emmrich F, Storch W, Von Baehr R, Schwenke H
出版信息
Folia Biol (Praha). 1975;21(3):155-9.
PMID:51802
Abstract
Lymphocytes from 22 healthy blood donors were tested for the presence of immunoglobulin determinants on their surfaces by indirect membrane immunofluorescence. The proportion of MemIF+ cells was, on the average, 8.7% (3-18) for IgM and 15.8% (8-28) for IgG. The small differences in the proportion of MemIF+ lymphocytes upon use of various anti-IgM sera could be attributed mainly to the different antibody concentrations. The importance of a quantitative characterization of the antisera used was pointed out.
摘要
通过间接膜免疫荧光法检测了22名健康献血者淋巴细胞表面免疫球蛋白决定簇的存在情况。MemIF+细胞的比例，IgM平均为8.7%（3%-18%），IgG平均为15.8%（8%-28%）。使用各种抗IgM血清时，MemIF+淋巴细胞比例的微小差异主要可归因于抗体浓度的不同。文中指出了对所用抗血清进行定量表征的重要性。
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