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神经元波形的最佳识别

Optimal recognition of neuronal waveforms.

作者信息

Roberts W M

出版信息

Biol Cybern. 1979 Nov 2;35(2):73-80. doi: 10.1007/BF00337433.

DOI:10.1007/BF00337433
PMID:518934
Abstract

Statistically optimal methods for identifying single unit activity in multiple unit recordings are discussed. These methods take into account both the nerve impulse waveforms and the firing patterns of the units. A generalized least-squares fit procedure is shown to be the optimal recognition scheme under some reasonable statistical assumptions, but the amount of computation becomes prohibitively large when the method is applied to the problem of sorting superimposed waveforms. A linear filter technique which relies on simultaneous recording from several electrodes is shown to give good separation of superimposed waveforms. An iterative recognition procedure can be applied to improve the results and reduce the number of recording electrodes required.

摘要

讨论了用于识别多单元记录中单个单元活动的统计最优方法。这些方法同时考虑了神经冲动波形和单元的放电模式。在一些合理的统计假设下,广义最小二乘拟合过程被证明是最优识别方案,但当该方法应用于叠加波形的分类问题时,计算量会变得大到令人望而却步。一种依赖于从多个电极同时记录的线性滤波技术被证明能很好地分离叠加波形。可以应用迭代识别过程来改善结果并减少所需的记录电极数量。

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Optimal recognition of neuronal waveforms.神经元波形的最佳识别
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2
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本文引用的文献

1
Neuronal spike trains and stochastic point processes. II. Simultaneous spike trains.神经元尖峰序列与随机点过程。II. 同步尖峰序列。
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Separation of multi-unit nerve impulse trains by a multi-channel linear filter algorithm.采用多通道线性滤波算法分离多单元神经冲动序列。
Brain Res. 1975 Aug 22;94(1):141-9. doi: 10.1016/0006-8993(75)90883-5.
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Mathematical analysis of optimal multichannel filtering for nerve signals.神经信号最优多通道滤波的数学分析
Biol Cybern. 1979 Feb 2;32(1):19-24. doi: 10.1007/BF00337447.
6
Computer separation of unitary spikes from whole-nerve recordings.从全神经记录中进行单位脉冲的计算机分离。
Brain Res. 1979 Jun 29;169(3):455-79. doi: 10.1016/0006-8993(79)90397-4.
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Application of optimal multichannel filtering to simulated nerve signals.最优多通道滤波在模拟神经信号中的应用。
Biol Cybern. 1979 Feb 2;32(1):25-33. doi: 10.1007/BF00337448.
8
Optimal filtering of nerve signals.神经信号的最佳滤波
Biol Cybern. 1977 Jul 8;27(1):41-8. doi: 10.1007/BF00357709.