Poulter N, Gabriel R
Curr Med Res Opin. 1979;6(3):207-8. doi: 10.1185/03007997909109423.
Five dialysis patients with residual hypertension were treated with a new sustained-release formulation of propranolol (160 mg per capsule) in a dosage of 1 to 2 capsules per day. Four of these patients developed persistent cold, numb, blue and clumsy fingers. The symptoms resolved when the drug was withdrawn.
五名患有残余高血压的透析患者接受了一种新的普萘洛尔缓释制剂(每粒胶囊含160毫克)治疗,剂量为每天1至2粒胶囊。其中四名患者出现了手指持续发冷、麻木、发蓝和活动不灵活的症状。停药后症状消失。