Cooke D M
Chemotherapy. 1979;25(6):356-61. doi: 10.1159/000237864.
A broad spectrum antibiotic, cephalexin, was used to treat 64 patients in whom the problems of age, underlying conditions and multiple drug therapy could adversely affect the outcome of antibiotic treatment. The majority of patients were given the antibiotic for a lower respiratory tract infection. Treatment was successful in 50 patients after 5 days, and in a further 3 after 10 days. In 25 patients another antibiotic had been used unsuccessfully to treat infection: 19 of these patients responded to cephalexin therapy. Minor gastro-intestinal side effects were reported in 4 patients.
一种广谱抗生素,头孢氨苄,被用于治疗64例患者,这些患者的年龄、基础疾病和多种药物治疗问题可能会对抗生素治疗结果产生不利影响。大多数患者因下呼吸道感染接受该抗生素治疗。50例患者在5天后治疗成功,另有3例在10天后治疗成功。在25例患者中,曾使用另一种抗生素治疗感染但未成功:其中19例患者对头孢氨苄治疗有反应。4例患者报告有轻微胃肠道副作用。