Kannel W B, McGee D L
Diabetes Care. 1979 Mar-Apr;2(2):120-6. doi: 10.2337/diacare.2.2.120.
This report examines prospectively, in the Framingham cohort, the relation of diabetes and impaired glucose tolerance to each of the cardiovascular sequelae, taking into account age, sex, and associated cardiovascular risk factors. The incidence of cardiovascular disease, as well as the levels of cardiovascular risk factors, were found to be higher in diabetic than in nondiabetic men and women. The relative impact of diabetes on coronary heart disease, peripheral vascular disease, or stroke incidence was the same in men and women, but for cardiovascular mortality and cardiac failure the impact is greater for women. Present evidence suggests that alleviation of associated cardiovascular risk factors is the most promising course in reducing cardiovascular sequelae in diabetic patients.
本报告前瞻性地研究了弗雷明汉队列中糖尿病和糖耐量受损与每种心血管后遗症之间的关系，并考虑了年龄、性别及相关心血管危险因素。结果发现，糖尿病患者中心血管疾病的发病率以及心血管危险因素水平均高于非糖尿病男性和女性。糖尿病对男性和女性冠心病、外周血管疾病或中风发病率的相对影响相同，但对于心血管死亡率和心力衰竭，女性受到的影响更大。目前的证据表明，减轻相关心血管危险因素是降低糖尿病患者心血管后遗症最有前景的方法。
