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巨细胞动脉炎中的肝脏改变:颞动脉炎和风湿性多肌痛(作者译)

[Liver changes in giant-cell arteritis: temporal arteritis and rheumatic polymyalgia (author's transl)].

作者信息

Gossmann H H, Dölle W, Korb G, Gerdes H, Martini G A

出版信息

Dtsch Med Wochenschr. 1979 Aug 24;104(34):1199-202. doi: 10.1055/s-0028-1129070.

Abstract

Liver changes were demonstrated in six elderly patients with giant-cell arteritis (temporal arteritis, three with polymyalgia). Histologically there was fatty infiltration in four and pericentral congestion in five, star-cell nodules in one and non-specific hepatitis in one. Bromsulphalein test was abnormal in all, but rapidly became normal as the arteritis was successfully treated with corticoids. The pathogenesis of the liver changes is unclear. The authors' observations and published reports suggest that they are typical of giant-cell arteritis; it is of importance in the diagnosis of underlying disease.

摘要

在6例巨细胞动脉炎(颞动脉炎,3例伴有风湿性多肌痛)老年患者中发现有肝脏改变。组织学检查显示,4例有脂肪浸润,5例有中央周围充血,1例有星状细胞结节,1例有非特异性肝炎。所有患者的酚四溴酞钠试验均异常,但随着用皮质类固醇成功治疗动脉炎,该试验迅速恢复正常。肝脏改变的发病机制尚不清楚。作者的观察结果和已发表的报告表明,这些改变是巨细胞动脉炎的典型表现;这对潜在疾病的诊断很重要。

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