Fong S, Zayas F, Oliva J, Alcorta L F, Lastra G
Eur J Nucl Med. 1979 Oct;4(5):327-31. doi: 10.1007/BF00263299.
A compound was synthetized, which by X-Ray diffraction studies proved to be hexahydrated sodium tripolyphosphate. By means of in vitro procedures, it was demonstrated that this compound was able to complex trivalent cations, and that 113mIn could be completely incorporated to it. In vivo studies in rats, and scans performed with this new radiopharmaceutical in humans showed its highly selective accumulation in metastasic bone tumors.
合成了一种化合物，通过X射线衍射研究证明其为六水合三聚磷酸钠。通过体外实验程序表明，该化合物能够络合三价阳离子，并且113m铟可以完全掺入其中。在大鼠体内进行的研究以及用这种新的放射性药物对人体进行的扫描显示，它在转移性骨肿瘤中具有高度选择性的积聚。
