Patel M C, Parab P B, Raikar U R, Ganatra R D
Nuklearmedizin. 1981 Apr;20(2):90-3.
Phenolphthalexon, a compound with iminodiacetic acid as a functional group, has been labelled with 113mIn to high chemical purity and its usefulness in studies of biliary excretion patency has been studied. Organ distribution of 113mInphenolphthalexon in mice was characterized by high liver uptake (50.8% of the administered dose after 5 min) and rapid clearance through the gall bladder. An animal model for studying obstruction of biliary excretion has been developed. Data on the kinetics of the radiopharmaceutical were obtained by collecting in-vivo data through an on-line computer.
酚酞磺酸钠，一种以亚氨基二乙酸为官能团的化合物，已用113m铟标记至高化学纯度，并对其在胆汁排泄通畅性研究中的效用进行了研究。113m铟标记的酚酞磺酸钠在小鼠体内的器官分布特点是肝脏摄取率高（5分钟后为给药剂量的50.8%），并通过胆囊快速清除。已建立了一个用于研究胆汁排泄梗阻的动物模型。通过在线计算机收集体内数据，获得了关于该放射性药物动力学的数据。
