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家兔甲状旁腺中¹²⁵I-甲苯胺蓝对⁷⁵Se-硒代蛋氨酸的剂量依赖性摄取。

Dose dependent uptake of 125I-toluidine blue of 75Se-selenomethionine in the parathyroids of rabbits.

作者信息

Normann E, Eide T, Lund P, Normann T

出版信息

Eur J Nucl Med. 1979 Dec;4(6):453-5. doi: 10.1007/BF00300845.

DOI:10.1007/BF00300845
PMID:520361
Abstract

Different dosages of 125I-toluidine blue and 75Se-selenomethionine were injected intravenously into rabbits, and the concentration of radioactivity was measured in the parathyroids and surrounding tissues. The response of i.v. injected glucagon was also determined. It was found that 0.16 mg 125I-toluidine blue gave a concentration ratio of parathyroid/thyroid and parathyroid/muscle which was significantly higher than both lower and higher doses at 1 minute after i.v. injection of the labelled dye. Glucagon had little or no effect on the uptake of 125I-toluidine blue and 75Se-selenomethionine.

摘要

将不同剂量的¹²⁵I-甲苯胺蓝和⁷⁵Se-硒代蛋氨酸静脉注射到兔子体内,然后测量甲状旁腺及周围组织中的放射性浓度。同时也测定了静脉注射胰高血糖素后的反应。结果发现,静脉注射标记染料1分钟后,0.16毫克¹²⁵I-甲苯胺蓝所产生的甲状旁腺/甲状腺和甲状旁腺/肌肉的浓度比显著高于较低和较高剂量。胰高血糖素对¹²⁵I-甲苯胺蓝和⁷⁵Se-硒代蛋氨酸的摄取几乎没有影响。

相似文献

1
Dose dependent uptake of 125I-toluidine blue of 75Se-selenomethionine in the parathyroids of rabbits.家兔甲状旁腺中¹²⁵I-甲苯胺蓝对⁷⁵Se-硒代蛋氨酸的剂量依赖性摄取。
Eur J Nucl Med. 1979 Dec;4(6):453-5. doi: 10.1007/BF00300845.
2
Uptake of 3H-labelled and 125I-labelled toluidine blue in hyperplastic parathyroids of rabbits.3H标记和125I标记的甲苯胺蓝在兔甲状旁腺增生组织中的摄取情况。
Acta Chir Scand. 1973;139(7):629-33.
3
Uptake of 125 I-labelled toluidine blue and ( 75 Se)-selenomethionine in the parathyroids of rabbits.125I标记的甲苯胺蓝和(75Se)-硒代蛋氨酸在兔甲状旁腺中的摄取
Scand J Clin Lab Invest. 1972 Sep;30(1):67-70. doi: 10.3109/00365517209081092.
4
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Scand J Clin Lab Invest. 1972;29(4):403-6. doi: 10.3109/00365517209080257.
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Ann Chir Gynaecol. 1976;65(4):249-52.
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本文引用的文献

1
Uptake of ³H-labelled commercial toluidine blue and subfractions (thionine, toluidine blue, and azur A) in the parathyroids of rabbits.³H 标记的商业甲苯胺蓝及其亚组分(硫堇、甲苯胺蓝和天青 A)在兔甲状旁腺中的摄取。
Scand J Clin Lab Invest. 1972;29(4):403-6. doi: 10.3109/00365517209080257.
2
Glucagon-induced hypocalcemia.
Metabolism. 1967 Jan;16(1):35-9. doi: 10.1016/0026-0495(67)90156-4.
3
Glucagon-induced hypocalcemia in man.胰高血糖素诱发的人体低钙血症。
J Clin Endocrinol Metab. 1969 Feb;29(2):213-8. doi: 10.1210/jcem-29-2-213.
4
Albumin standards and the measurement of serum albumin with bromcresol green.白蛋白标准品及用溴甲酚绿测定血清白蛋白
Clin Chim Acta. 1971 Jan;31(1):87-96. doi: 10.1016/0009-8981(71)90365-2.
5
Peroperative staining of parathyroid adenomas by intravenous infusion of toluidine blue.通过静脉输注甲苯胺蓝对甲状旁腺腺瘤进行术中染色。
Acta Chir Scand. 1971;137(3):213-9.
6
Parathyroid scanning with 75 Se-selenomethionine and glucagon stimulation.使用75硒-硒代蛋氨酸进行甲状旁腺扫描及胰高血糖素刺激试验。
J Nucl Med. 1971 Nov;12(11):751-3.
7
Uptake of 125 I-labelled toluidine blue and ( 75 Se)-selenomethionine in the parathyroids of rabbits.125I标记的甲苯胺蓝和(75Se)-硒代蛋氨酸在兔甲状旁腺中的摄取
Scand J Clin Lab Invest. 1972 Sep;30(1):67-70. doi: 10.3109/00365517209081092.
8
Uptake of 3H-labelled and 125I-labelled toluidine blue in hyperplastic parathyroids of rabbits.3H标记和125I标记的甲苯胺蓝在兔甲状旁腺增生组织中的摄取情况。
Acta Chir Scand. 1973;139(7):629-33.
9
Clinical radionuclide-imaging of enlarged parathyroids with 131-I-toluidine blue.用131-I-甲苯胺蓝对甲状旁腺肿大进行临床放射性核素显像
Acta Chir Scand. 1974;140(7):517-22.
10
Use of 131I-toluidine blue in radionuclide imaging of enlarged parathyroid glands.131I-甲苯胺蓝在甲状旁腺肿大的放射性核素成像中的应用。
Ann Chir Gynaecol. 1976;65(4):249-52.