Normann E, Rootwelt K, Solheim D, Sodal G
Ann Chir Gynaecol. 1976;65(4):249-52.
Parathyroid scintigraphy with 131I-labelled toluidine blue was performed in 40 patients, 30 of whom were operated for suspected hyperparathyroidism. Hyperplastic glands or adenomas could be localized by scintigraphy in 18 of 27 patients who proved to have hyperparathyroidism. The correlation between scintigraphy and operative finding was always correct when the parathyroids weighed more than 2 g. Scintigraphy was correctly negative in one, falsely negative in 6, and falsely positive in 5 of the operated patients. In a group of 10 unoperated patients, scintigraphy was positive in one of the 3 patients with suspected hyperparathyroidism, but negative in the others. Although 131I-toluidine blue is not ideal as a scintigraphic agent for the parathyroids, we are of the opinion that it represents an improvement compared with 75Se-selenomethionine.
对40例患者进行了131I标记甲苯胺蓝甲状旁腺闪烁扫描，其中30例因疑似甲状旁腺功能亢进接受了手术。在27例经证实患有甲状旁腺功能亢进的患者中，闪烁扫描能定位增生性腺或腺瘤的有18例。当甲状旁腺重量超过2克时，闪烁扫描与手术结果之间的相关性总是正确的。在接受手术的患者中，闪烁扫描结果正确为阴性的有1例，假阴性的有6例，假阳性的有5例。在一组10例未接受手术的患者中，3例疑似甲状旁腺功能亢进的患者中有1例闪烁扫描呈阳性，其他患者为阴性。虽然131I - 甲苯胺蓝作为甲状旁腺闪烁造影剂并不理想，但我们认为与75Se - 硒代蛋氨酸相比，它是一种改进。
