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Glycine stimulates the spontaneous release of newly synthesized 3H-dopamine in rat striatal slices.

作者信息

Giorguieff-Chesselet M F, Kemel M L, Wandscheer D, Glowinski J

出版信息

Eur J Pharmacol. 1979 Nov 23;60(1):10U-4. doi: 10.1016/0014-2999(79)90057-8.

DOI:10.1016/0014-2999(79)90057-8
PMID:520411
Abstract

Glycine (5 X 10(-5) M) stimulated the spontaneous release of 3H-DA continuously synthesized from 3H-tyrosine in striatal slices. This effect was calcium-dependent and significantly reduced in the presence of strychnine (10(-5) M). The glycine-evoked release of 3H-DA was no longer seen in the presence of tetrodotoxin (5 X 10(-7) M).

摘要

相似文献

1
Glycine stimulates the spontaneous release of newly synthesized 3H-dopamine in rat striatal slices.
Eur J Pharmacol. 1979 Nov 23;60(1):10U-4. doi: 10.1016/0014-2999(79)90057-8.
2
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Glycine-evoked release of [3H]acetylcholine from rat striatal slices is independent of the NMDA receptor.甘氨酸诱发大鼠纹状体切片释放[3H]乙酰胆碱与N-甲基-D-天冬氨酸受体无关。
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Role of various amino acids on the modulation of dopamine release from nigro-striatal dopaminergic neurones.
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引用本文的文献

1
Glycine Signaling in the Framework of Dopamine-Glutamate Interaction and Postsynaptic Density. Implications for Treatment-Resistant Schizophrenia.多巴胺-谷氨酸相互作用及突触后致密物框架下的甘氨酸信号传导。对难治性精神分裂症的意义。
Front Psychiatry. 2020 May 14;11:369. doi: 10.3389/fpsyt.2020.00369. eCollection 2020.
2
Glycine-induced changes in acetylcholine release from guinea-pig brain slices.甘氨酸诱导的豚鼠脑片乙酰胆碱释放变化。
Br J Pharmacol. 1983 Jun;79(2):623-8. doi: 10.1111/j.1476-5381.1983.tb11038.x.
3
Glycine-evoked release of [3H]acetylcholine from rat striatal slices is independent of the NMDA receptor.
甘氨酸诱发大鼠纹状体切片释放[3H]乙酰胆碱与N-甲基-D-天冬氨酸受体无关。
Naunyn Schmiedebergs Arch Pharmacol. 1988 May;337(5):552-5. doi: 10.1007/BF00182730.