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Potentiation of levodopa effect by intravenous L-prolyl-L-leucyl-glycine amide in man.

作者信息

Barbeau A

出版信息

Lancet. 1975 Oct 11;2(7937):683-4. doi: 10.1016/s0140-6736(75)90778-3.

DOI:10.1016/s0140-6736(75)90778-3
PMID:52054
Abstract

L-prolyl-L-leucyl-glycine amide (P.L.G.) has melanocyte-stimulating-hormone-inhibitory hormone (M.I.F.) activity. When injected intravenously as a bolus of 200 mg, it greatly potentiated the effect of an oral levodopa dose upon motor performance objectively measured by a battery of tests. This amelioration in motility was accompanied by improvement in intellectual functioning.

摘要

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