D-异抗坏血酸和水合甜菜碱单独及联合使用对正常细胞和恶性细胞的体外作用
In vitro effect of D-isoascorbic acid and betaine hydrate alone and in combination on normal and malignant cells.
作者信息
Freidel J F, Fardon J C, Tsuchiya Y, Nutini L G
出版信息
Exp Cell Biol. 1979;47(6):463-9. doi: 10.1159/000162964.
PMID:520651
Abstract
D-Isoascorbic acid, an isomer of vitamin C, and betaine hydrate (quaternary amine) were found to inhibit mitoses of sarcoma 37, Ehrlich carcinoma, and L1210 leukemia cells in vitro. However, the combined effect of these compounds produced a greater inhibitory activity than when either was administered individually.
摘要
D-异抗坏血酸是维生素C的一种异构体，发现它与水合甜菜碱（季胺）在体外能抑制肉瘤37、艾氏癌和L1210白血病细胞的有丝分裂。然而，这些化合物联合使用时产生的抑制活性比单独使用任一种时都更强。
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