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西澳大利亚1956 - 1975年脑瘫的流行病学研究。I:脑瘫总发病率及相关因素的变化

An epidemiological study of cerebral palsy in Western Australia, 1956-1975. I: Changes in total incidence of cerebral palsy and associated factors.

作者信息

Stanley F J

出版信息

Dev Med Child Neurol. 1979 Dec;21(6):701-13. doi: 10.1111/j.1469-8749.1979.tb01691.x.

Abstract

Patterns in the incidence of cerebral palsy are described over a 20-year period in Western Australia. The incidence rose to a peak between 1966 and 1970, then fell again. This pattern was particularly marked in the spastic syndromes and was seen in both sexes, in each maternal age and parity group, in each IQ group, in both multiple and single births, and in infants born in metropolitan (but not rural) areas. Improvement was more marked in heavier than in lighter infants. Since 1968 the male rate has fallen more quickly than that for females. The risk of cerebral palsy with high maternal age declined, but it remained high in relation to high parities. There were marked reductions in the proportions of older and higher-parity mothers in Western Australia over the study period, and in the proportion of multiple births. There was also a shift toward heavier babies from 1968 to 1975. Social-class information was not available. The data indicate that factors in addition to changes in perinatal care were operating to improve neonatal outcome in terms of long-term handicap in Western Australia.

摘要

本文描述了西澳大利亚州20年间脑瘫发病率的变化模式。发病率在1966年至1970年间升至峰值,随后再次下降。这种模式在痉挛综合征中尤为明显,在各个性别、各个产妇年龄和胎次组、各个智商组、多胞胎和单胞胎以及大都市(而非农村)地区出生的婴儿中均可见到。体重较重的婴儿比体重较轻的婴儿改善更为明显。自1968年以来,男性发病率下降速度比女性更快。高龄产妇患脑瘫的风险有所下降,但与高胎次产妇相比仍处于高位。在研究期间,西澳大利亚州高龄和高胎次母亲的比例以及多胞胎的比例均显著下降。1968年至197年期间,出生婴儿体重也有向更重方向转变的趋势。社会阶层信息无法获取。数据表明,除围产期护理变化外,还有其他因素在改善西澳大利亚州新生儿长期残疾方面发挥作用。

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