Kantrowitz P A, Fleischli D J, Butler W T
Gastroenterology. 1969 Oct;57(4):424-30.
A 35-year-old man with idiopathic hypoparathyroidism and moniliasis developed progressive dysphagia and weight loss. Diagnostic studies established the presence of esophageal moniliasis. Therapy with a viscous suspension of nystatin resulted in rapid clinical improvement; prolonged administration of the drug was associated with progressive widening of a narrowed segment of esophagus and complete disappearance of dysphagia. The chemotherapy of esophageal moniliasis is discussed in the light of current knowledge of the pharmacological action of nystatin.
一名患有特发性甲状旁腺功能减退症和念珠菌病的35岁男子出现进行性吞咽困难和体重减轻。诊断性检查确定存在食管念珠菌病。用制霉菌素粘性混悬液治疗后临床症状迅速改善;长期使用该药物与食管狭窄段逐渐增宽及吞咽困难完全消失有关。根据目前对制霉菌素药理作用的认识,对食管念珠菌病的化疗进行了讨论。