Epstein F H, Ostrander L D
Prog Cardiovasc Dis. 1971 Jan;13(4):324-42. doi: 10.1016/s0033-0620(71)80010-5.
Current views on the usefulness of pre-clinical markers to detect susceptibility toward coronary heart disease have been presented, including the role of the hyperlipidemias, hypertension, hyperglycemia, obesity, family history and several other personal attributes. In addition, various clinical, electrocardiographic and other indices of early clinical disease serve as premonitory warning signals toward myocardial infarction and sudden death. Individuals harboring one or more of these risk factors should be detected and protected by means of preventive measures.