Nagasawa K, Inoue Y, Tokuyasu T
J Biochem. 1979 Nov;86(5):1323-9. doi: 10.1093/oxfordjournals.jbchem.a132648.
By heating the pyridinium salts of chondroitin 4- and 6-sulfates in dimethyl sulfoxide containing 10% of water or methanol at 80 degrees C for 1--5 h, several chondroitin preparations with sulfur contents of 0.02--1.05% were prepared in 83--96% yields, respectively. Chemical properties of the preparations, such as degrees of desulfation and of depolymerization, were compared with those of the products obtained by the previously described methods.
通过在含有10%水或甲醇的二甲基亚砜中于80℃将硫酸软骨素4-硫酸酯和6-硫酸酯的吡啶盐加热1至5小时，分别以83%至96%的产率制备了几种硫含量为0.02%至1.05%的软骨素制剂。将这些制剂的化学性质，如脱硫程度和解聚程度，与通过先前描述的方法获得的产物的化学性质进行了比较。
