透明质酸和硫酸软骨素的二级结构。二甲基亚砜溶液中NH信号的1H核磁共振研究。
Secondary structures of hyaluronate and chondroitin sulphates. A 1H n.m.r. study of NH signals in dimethyl sulphoxide solution.
作者信息
Scott J E, Heatley F, Moorcroft D, Olavesen A H
出版信息
Biochem J. 1981 Dec 1;199(3):829-32. doi: 10.1042/bj1990829.
Abstract
1H n.m.r. spectra in [2H6]dimethyl sulphoxide of dodecyltrimethylammonium salts of chondroitin sulphates and hyaluronate, or sodium salts of oligomers from hyaluronate, showed unambiguous NH signals. The acetamido NH occurs in two different environments: environment I ('normal') in simple sugars, and environment II (hydrogen-bonded NH) appearing in tri- or tetrasaccharides, indicating a secondary structure in hyaluronate (and some chondroitin sulphates) involving a hydrogen-bonded acetamido NH.
摘要
硫酸软骨素和透明质酸的十二烷基三甲基铵盐，或透明质酸低聚物的钠盐在[2H6]二甲基亚砜中的1H核磁共振谱显示出明确的NH信号。乙酰氨基NH出现在两种不同的环境中：简单糖类中的环境I（“正常”），以及三糖或四糖中出现的环境II（氢键结合的NH），这表明透明质酸（以及一些硫酸软骨素）中存在涉及氢键结合的乙酰氨基NH的二级结构。
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