Paths of carbon in gluconeogenesis and lipogenesis: the role of mitochondria in supplying precursors of phosphoenolpyruvate.
作者信息
Lardy H A, Paetkau V, Walter P
出版信息
Proc Natl Acad Sci U S A. 1965 Jun;53(6):1410-5. doi: 10.1073/pnas.53.6.1410.
Abstract
摘要
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本文引用的文献
1
The Pathway of Gluconeogenesis in Liver.肝脏中糖异生的途径。
Science. 1964 May 1;144(3618):564. doi: 10.1126/science.144.3618.564-b.
2
Oxidative phosphorylations; rôle of inorganic phosphate and acceptor systems in control of metabolic rates.氧化磷酸化；无机磷酸盐和受体系统在代谢速率控制中的作用。
J Biol Chem. 1952 Mar;195(1):215-24.
3
4
METABOLIC CONTROL OF ENZYMES INVOLVED IN LIPOGENESIS AND GLUCONEOGENESIS.脂肪生成和糖异生相关酶的代谢调控
Biochemistry. 1964 Nov;3:1687-92. doi: 10.1021/bi00899a015.
5
MALIC ENZYME AND LIPOGENESIS.苹果酸酶与脂肪生成
Proc Natl Acad Sci U S A. 1964 Nov;52(5):1255-63. doi: 10.1073/pnas.52.5.1255.
6
PYRUVATE METABOLISM AND CONTROL: FACTORS AFFECTING PYRUVIC CARBOXYLASE ACTIVITY.丙酮酸代谢与调控：影响丙酮酸羧化酶活性的因素
Science. 1964 Jul 3;145(3627):58-60. doi: 10.1126/science.145.3627.58.
7
[CORTISOL-INDUCED INCREASE IN PYRUVATE CARBOXYLASE ACTIVITY IN THE RAT LIVER].[皮质醇诱导大鼠肝脏丙酮酸羧化酶活性增加]
Biochim Biophys Acta. 1963 Oct 1;77:345-8. doi: 10.1016/0006-3002(63)90509-2.
8
METABOLIC AND HORMONAL CONTROL OF PHOSPHOENOLPYRUVATE CARBOXYKINASE AND MALIC ENZYME IN RAT LIVER.大鼠肝脏中磷酸烯醇丙酮酸羧激酶和苹果酸酶的代谢与激素调控
J Biol Chem. 1963 Oct;238:3188-92.
9
PYRUVATE CARBOXYLASE. I. NATURE OF THE REACTION.丙酮酸羧化酶。一、反应性质
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Studies on experimental diabetes. II. Carbon dioxide fixation.实验性糖尿病研究。II. 二氧化碳固定
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