Sauer R, Hünig R
Strahlentherapie. 1975 Aug;150(2):109-20.
Experiences are reported obtained with radiation therapy of brain metastases in 121 patients during the last 15 years. The treatment to lesser extent aimed at prolongation of survival but much more at the attempt to alleviate troubles and to spare pain. The indication thus involved medical points of view as well as ethical ones. The radiotherapy of cerebral metastases comprises the whole cranial volume and requires a focal dose of minimally 4000 R within four weeks. In 53% of the patients, the regression of neurological symptoms was considerable, in 18% even complete, partly beginning already after a few days of treatment. The number of recurrences was small. Under conditions of rigorous indication, the radiation therapy of brain metastases offers a rewarding palliative measure.
报告了过去15年中对121例脑转移瘤患者进行放射治疗的经验。治疗在较小程度上旨在延长生存期,但更多的是试图减轻不适和缓解疼痛。因此,适应症涉及医学观点以及伦理观点。脑转移瘤的放射治疗包括整个颅腔容积,并且需要在四周内给予至少4000伦琴的局部剂量。53%的患者神经症状有显著缓解,18%的患者甚至完全缓解,部分患者在治疗几天后就开始缓解。复发的病例数较少。在严格掌握适应症的情况下,脑转移瘤的放射治疗是一种有效的姑息治疗措施。