Maass B, Baumgärtl H, Lübbers D W
Laryngol Rhinol Otol (Stuttg). 1979 Aug;58(8):665-70.
Oxygen partial pressure was measured in the endolymph area of the cat cochlea under conditions of hemorrhagic hypotension. The experiments took place after unilateral upper cervical sympathectomy and under control conditions. The pO2-measurements were carried out with the aid of polarographic micro-coaxial needle electrodes according to Baumgärtl and Lübbers (1, 2, 3). In animals which had not been sympathectomized, the cochlear pO2 decreased continuously parallely to blood pressure, with the beginning of bleeding. After sympathectomy pO2-decrease in cochlea only occurred at substantially lower aortal blood pressure. This allows the following conclusions: 1. Under conditions of hemorrhagic shock the blood flow of the inner ear is not as much included in central circulation as brain and heart. 2. The blood pressure dependence of the inner ear blood flow depends on the sympathetic innervation, it can practically be abolished up to a blood pressure of 65 mm Hg by denervation. 3. It is being discussed, which therapeutic consequences can be drawn from the evident influence of the sympathetic innervation on the inner ear blood flow.
在出血性低血压条件下,测量猫耳蜗内淋巴区域的氧分压。实验在单侧颈上神经节切除术后以及对照条件下进行。根据鲍姆加特尔和吕伯斯(1,2,3)的方法,借助极谱微同轴针电极进行pO₂测量。在未进行交感神经切除术的动物中,随着出血开始,耳蜗pO₂与血压平行持续下降。交感神经切除术后,耳蜗pO₂仅在主动脉血压显著降低时才下降。由此可得出以下结论:1. 在出血性休克条件下,内耳的血流不像脑和心脏那样大量参与体循环。2. 内耳血流对血压的依赖性取决于交感神经支配,去神经后在血压降至65 mmHg时实际上可消除这种依赖性。3. 正在讨论交感神经支配对内耳血流的明显影响可得出哪些治疗后果。