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[交感神经切除术对出血性低血压条件下耳蜗氧分压(pO2)的影响(作者译)]

[The effect of sympathectomy on the cochlear oxygen pressure (pO2) under conditions of haemorrhagic hypotension (author's transl)].

作者信息

Maass B, Baumgärtl H, Lübbers D W

出版信息

Laryngol Rhinol Otol (Stuttg). 1979 Aug;58(8):665-70.

PMID:522582
Abstract

Oxygen partial pressure was measured in the endolymph area of the cat cochlea under conditions of hemorrhagic hypotension. The experiments took place after unilateral upper cervical sympathectomy and under control conditions. The pO2-measurements were carried out with the aid of polarographic micro-coaxial needle electrodes according to Baumgärtl and Lübbers (1, 2, 3). In animals which had not been sympathectomized, the cochlear pO2 decreased continuously parallely to blood pressure, with the beginning of bleeding. After sympathectomy pO2-decrease in cochlea only occurred at substantially lower aortal blood pressure. This allows the following conclusions: 1. Under conditions of hemorrhagic shock the blood flow of the inner ear is not as much included in central circulation as brain and heart. 2. The blood pressure dependence of the inner ear blood flow depends on the sympathetic innervation, it can practically be abolished up to a blood pressure of 65 mm Hg by denervation. 3. It is being discussed, which therapeutic consequences can be drawn from the evident influence of the sympathetic innervation on the inner ear blood flow.

摘要

在出血性低血压条件下,测量猫耳蜗内淋巴区域的氧分压。实验在单侧颈上神经节切除术后以及对照条件下进行。根据鲍姆加特尔和吕伯斯(1,2,3)的方法,借助极谱微同轴针电极进行pO₂测量。在未进行交感神经切除术的动物中,随着出血开始,耳蜗pO₂与血压平行持续下降。交感神经切除术后,耳蜗pO₂仅在主动脉血压显著降低时才下降。由此可得出以下结论:1. 在出血性休克条件下,内耳的血流不像脑和心脏那样大量参与体循环。2. 内耳血流对血压的依赖性取决于交感神经支配,去神经后在血压降至65 mmHg时实际上可消除这种依赖性。3. 正在讨论交感神经支配对内耳血流的明显影响可得出哪些治疗后果。

相似文献

1
[The effect of sympathectomy on the cochlear oxygen pressure (pO2) under conditions of haemorrhagic hypotension (author's transl)].[交感神经切除术对出血性低血压条件下耳蜗氧分压(pO2)的影响(作者译)]
Laryngol Rhinol Otol (Stuttg). 1979 Aug;58(8):665-70.
2
[Local pO2 measurements in the cochlear perilymph of guinea pigs in oxygen and oxygen/carbon dioxide breathing (author's transl)].豚鼠在吸氧及吸氧气/二氧化碳混合气时耳蜗外淋巴局部氧分压的测定(作者译)
Laryngol Rhinol Otol (Stuttg). 1979 Sep;58(9):731-6.
3
Renal oxygen and lactate metabolism in hemorrhagic shock. An experimental study.失血性休克时肾脏的氧和乳酸代谢:一项实验研究
Acta Chir Scand Suppl. 1984;518:1-44.
4
[Blood supply of the internal ear. Anatomico-functional considerations].[内耳的血液供应。解剖学与功能方面的考量]
HNO. 1982 Oct;30(10):355-64.
5
[Oxygen partial pressure measurements in the perilymph and scala tympani in normo- and hyperbaric conditions. An animal experiment study].[正常和高压条件下外淋巴和鼓阶内氧分压的测量。一项动物实验研究]
HNO. 1988 Sep;36(9):363-6.
6
Cerebral, coronary, and renal blood flows during hemorrhagic hypotension in anesthetized miniature swine.麻醉状态下小型猪失血性低血压时的脑、冠状动脉及肾血流量
Adv Shock Res. 1983;9:189-201.
7
[Local pO2- and pH2-measurements with needle electrodes for the examination of the hydrogen maintenance and microcirculation of the cochleae (author's transl)].[使用针电极进行局部氧分压和氢分压测量以检查耳蜗的氢维持和微循环(作者译)]
Arch Otorhinolaryngol. 1976 Nov 15;214(2):109-24. doi: 10.1007/BF00453607.
8
Plasma renin activity, renal artery blood flow and cortical tissue oxygen tensionin haemorrhagic hypotension.
Ann Chir Gynaecol. 1977;66(2):94-7.
9
[Adaptive function of the sympathetic innervation of cerebral vessels following rapid changes in systemic arterial pressure].
Biull Eksp Biol Med. 1980 Nov;90(11):543-6.
10
Oxygen reserve and autoregulation in the cochlea.
Acta Otolaryngol. 1977 Jan-Feb;83(1-2):146-52. doi: 10.3109/00016487709128825.

引用本文的文献

1
Hydrogen clearance and cochlear microcirculation at different levels of blood pressure.不同血压水平下的氢清除率与耳蜗微循环
Arch Otorhinolaryngol. 1984;240(3):295-310. doi: 10.1007/BF00453385.