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[正常和高压条件下外淋巴和鼓阶内氧分压的测量。一项动物实验研究]

[Oxygen partial pressure measurements in the perilymph and scala tympani in normo- and hyperbaric conditions. An animal experiment study].

作者信息

Lamm C, Walliser U, Schumann K, Lamm K

机构信息

Abteilung für Experimentelle Otologie der HNO-Klinik der Medizinischen Hochschule Hannover.

出版信息

HNO. 1988 Sep;36(9):363-6.

PMID:3170281
Abstract

The purpose of this study was to examine the influence of hyperbaric oxygen on the oxygen tension (pO2) in the normal inner ear. We examined 16 anaesthetised guinea pigs by means of an oxygen-sensitive micro-coaxial needle electrode, using the method described by Baumgaertl and Luebbers. In all animals the pO2 in the perilymph of the scala tympani fell by 34% of the original value during insertion of the sensor into the scala tympani. After we had flooded the hyperbaric chamber with pure oxygen under normobaric conditions the pO2 increased by 244.3% of the original values. Furthermore the pO2 increased by 9.4 times the original values during hyperbaric oxygen at 1.6 bar.

摘要

本研究的目的是检测高压氧对正常内耳氧分压(pO2)的影响。我们采用鲍姆加特尔和勒贝斯描述的方法,通过氧敏感微同轴针电极对16只麻醉的豚鼠进行了检测。在所有动物中,将传感器插入鼓阶时,鼓阶外淋巴中的pO2下降至原始值的34%。在常压条件下用纯氧充满高压舱后,pO2增加至原始值的244.3%。此外,在1.6巴的高压氧环境下,pO2增加至原始值的9.4倍。

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