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单纯疱疹病毒（HSV）对器官型神经细胞培养物的感染。2型病毒而非1型病毒感染的细胞细胞核中出现管状结构。

Herpes simplex virus (HSV) infection of organotypic nerve cell cultures. Tubule-like structures in the nuclei of cells infected with type 2 but not with type 1 virus.

作者信息

Ecob-Johnston M S, Whetsell W O

出版信息

Acta Neuropathol. 1979 Dec;48(3):219-21. doi: 10.1007/BF00690523.

DOI:10.1007/BF00690523
PMID:525261
Abstract

In HSV-2 infected cultures, intranuclear tubule-like structures were found more commonly in fibroblasts and central nervous system (CNS) neurons than in oligodendrocytes, astrocytes, satellite and Schwann cells, but were found least often in peripheral neurons.

摘要

在单纯疱疹病毒2型（HSV - 2）感染的培养物中，细胞核内管状样结构在成纤维细胞和中枢神经系统（CNS）神经元中比在少突胶质细胞、星形胶质细胞、卫星细胞和雪旺细胞中更常见，但在外周神经元中出现的频率最低。

相似文献

1
Herpes simplex virus (HSV) infection of organotypic nerve cell cultures. Tubule-like structures in the nuclei of cells infected with type 2 but not with type 1 virus.单纯疱疹病毒（HSV）对器官型神经细胞培养物的感染。2型病毒而非1型病毒感染的细胞细胞核中出现管状结构。
Acta Neuropathol. 1979 Dec;48(3):219-21. doi: 10.1007/BF00690523.
2
Herpes simplex virus types 1 and 2 in organotypic cultures of mouse central and peripheral nervous system. 2. Electron microscopic observations of myelin degeneration.单纯疱疹病毒1型和2型在小鼠中枢和外周神经系统的器官型培养物中的研究。2. 髓鞘变性的电子显微镜观察
J Neuropathol Exp Neurol. 1979 Jan;38(1):10-8. doi: 10.1097/00005072-197901000-00002.
3
Host-cell response to herpes virus infection in central and peripheral nervous tissue in vitro.
J Gen Virol. 1979 Sep;44(3):747-57. doi: 10.1099/0022-1317-44-3-747.
4
The relationship of astrocytes and macrophages to CNS demyelination after experimental herpes simplex virus infection.实验性单纯疱疹病毒感染后星形胶质细胞和巨噬细胞与中枢神经系统脱髓鞘的关系。
J Neuropathol Exp Neurol. 1981 Jul;40(4):369-79. doi: 10.1097/00005072-198107000-00002.
5
Wolman's disease: ultrastructural evidence of lipid accumulation in central and peripheral nervous systems.
Acta Neuropathol. 1979 Jan 12;45(1):37-42. doi: 10.1007/BF00691802.
6
Herpes simplex virus types 1 and 2 in organotypic cultures of mouse central and peripheral nervous system. I. Light microscopic observations of myelin degeneration.单纯疱疹病毒1型和2型在小鼠中枢和外周神经系统器官型培养物中的研究。I. 髓鞘变性的光镜观察
J Neuropathol Exp Neurol. 1978 Sep;37(5):518-30. doi: 10.1097/00005072-197809000-00007.
7
Herpes simplex virus in the vestibular ganglion and the geniculate ganglion-role of loose myelin.单纯疱疹病毒在前庭神经节和膝状神经节中的作用——疏松髓鞘的作用
J Neurocytol. 2001 Aug;30(8):685-93. doi: 10.1023/a:1016577700280.
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Upregulation of class I major histocompatibility complex gene expression in primary sensory neurons, satellite cells, and Schwann cells of mice in response to acute but not latent herpes simplex virus infection in vivo.在体内，小鼠的初级感觉神经元、卫星细胞和施万细胞中，I类主要组织相容性复合体基因表达上调，以响应急性而非潜伏性单纯疱疹病毒感染。
J Exp Med. 1994 Sep 1;180(3):841-50. doi: 10.1084/jem.180.3.841.
9
Virus-induced demyelination in herpes simplex virus-infected mice.单纯疱疹病毒感染小鼠中病毒诱导的脱髓鞘
J Neurol Sci. 1982 Feb;53(2):205-16. doi: 10.1016/0022-510x(82)90006-5.
10
Multifocal CNS demyelination following peripheral inoculation with herpes simplex virus type 1.外周接种1型单纯疱疹病毒后发生的多灶性中枢神经系统脱髓鞘病变。
Ann Neurol. 1987 Jul;22(1):52-9. doi: 10.1002/ana.410220113.

本文引用的文献

1
Similarities and Differences in the Development of Laboratory Strains and Freshly Isolated Strains of Herpes Simplex Virus in HEp-2 Cells: Electron Microscopy.单纯疱疹病毒实验室毒株和新分离毒株在人喉表皮癌细胞（HEp-2细胞）中生长的异同：电子显微镜观察
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Intranuclear formation of filaments in herpesvirus hominis infection of mice.
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Herpesvirus type 2 isolated from cervical tumor cells grown in tissue culture.从组织培养中生长的宫颈肿瘤细胞中分离出的2型疱疹病毒。
Science. 1971 Nov 12;174(4010):704-7. doi: 10.1126/science.174.4010.704.
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Experimental herpes simplex encephalitis: early neuropathologic changes.实验性单纯疱疹性脑炎：早期神经病理学变化
J Neuropathol Exp Neurol. 1970 Jan;29(1):89-104. doi: 10.1097/00005072-197001000-00007.
5
Photo-reconstituted collagen gel for tissue culture substrates.用于组织培养基质的光重组胶原凝胶。
Exp Cell Res. 1973 Feb;76(2):447-8. doi: 10.1016/0014-4827(73)90399-6.
6
Evidence that neurons harbor latent herpes simplex virus.神经元携带潜伏性单纯疱疹病毒的证据。
Infect Immun. 1974 May;9(5):946-51. doi: 10.1128/iai.9.5.946-951.1974.
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Characterization of genital strains of Herpesvirus hominis.人疱疹病毒生殖器毒株的特征描述。
Br J Vener Dis. 1973 Aug;49(4):385-90. doi: 10.1136/sti.49.4.385.
8
Hexagonal arrangement of filaments in herpes simplex virus type 2-infected cells.2型单纯疱疹病毒感染细胞中细丝的六边形排列。
Jpn J Microbiol. 1973 May;17(3):230-2. doi: 10.1111/j.1348-0421.1973.tb00733.x.
9
Herpes virus hominis type 2 and intranuclear tubular structures in organized nervous tissue cultures.
Acta Neuropathol. 1972;22(2):170-9. doi: 10.1007/BF00688783.
10
Filamentous structures of type 2 Herpesvirus hominis infection of the chorioallantoic membrane.人疱疹病毒2型感染绒毛尿囊膜的丝状结构。
J Virol. 1969 Feb;3(2):228-32. doi: 10.1128/JVI.3.2.228-232.1969.