Couch E F, Nahmias A J
J Virol. 1969 Feb;3(2):228-32. doi: 10.1128/JVI.3.2.228-232.1969.
In view of recent recognition of the existence of two Herpesvirus hominis (HVH) types with antigenic and biological differences, an electron microscopic study was undertaken of pocks produced on the choriallantoic membrane of embryonated eggs after infection with type 1 and type 2 HVH strains. Besides the typical morphological features of herpesvirus infection noted by several investigators, it was observed that type 2 HVH also produced microtubules measuring approximately 19 nm in both nucleus and cytoplasm. Although the nature of these filamentous structures is still unclear, consideration is given in this paper to the possibility that they may represent viral structural subunits, aberrant forms or neoantigens.
鉴于最近认识到存在两种具有抗原和生物学差异的人疱疹病毒（HVH）类型，我们对1型和2型HVH毒株感染后在鸡胚绒毛尿囊膜上产生的痘疱进行了电子显微镜研究。除了几位研究人员指出的疱疹病毒感染的典型形态特征外，还观察到2型HVH在细胞核和细胞质中均产生了直径约19nm的微管。尽管这些丝状结构的性质仍不清楚，但本文考虑了它们可能代表病毒结构亚基、异常形式或新抗原的可能性。
