Rigolot J C, Vergnes Y, Bouket J L, Gauthier-Lafaye P
Anesth Analg (Paris). 1979;36(7-8):317-21.
In that study we compared the analgesic effects of equianalgesic doses of buprenorphine and morphine taken as the narcotic of reference. The experiment has been undertaken in ten adults having severe cancer pain. The results have been analysed by statistical non parametric tests. We found that buprenorphine and morphine have the same pattern of action despite the fact that intramuscular buprenorphine has a clinical duration of approximately 9 hours.
在该研究中，我们比较了等效镇痛剂量的丁丙诺啡和吗啡（作为参考麻醉剂）的镇痛效果。实验在10名患有重度癌痛的成年人中进行。结果采用统计学非参数检验进行分析。我们发现，尽管肌肉注射丁丙诺啡的临床持续时间约为9小时，但丁丙诺啡和吗啡具有相同的作用模式。
