Ventafridda V, De Conno F, Guarise G, Tamburini M, Savio G
Arzneimittelforschung. 1983;33(4):587-90.
Buprenorphine appears to have an analgesic effect (evaluated after a week of treatment) statistically superior to that of the comparative drug. On the whole, during buprenorphine treatment the normal activities of life of the individual patient improved. The percentage incidence of the side-effects is similar for the two drugs. Buprenorphine, however, caused less intense side-effects than pentazocine.
丁丙诺啡似乎具有镇痛作用(治疗一周后评估),在统计学上优于对照药物。总体而言,在丁丙诺啡治疗期间,个体患者的正常生活活动有所改善。两种药物的副作用发生率相似。然而,丁丙诺啡引起的副作用比喷他佐辛轻。